Table S1. Gene expression profiles of SC from EAE mice

   

Expression level normalized by ß-actin

Ratio of gene expression

   

Before onset

After onset

PAFR-WT/PAFR-KO

Before/after onset

Genebank

Gene name

PAFR-WT

PAFR-KO

PAFR-WT

PAFR-KO

Before the onset

After the onset

PAFR-WT

PAFR-KO

NM_011798

CXCR1

0.431

0.458

0.719

0.719

0.94

1.00

1.67

1.57

U51717

CCR2

0.166

0.109

0.349

0.332

1.52

1.05

2.11

3.04

D83648

CCR5

0.144

0.112

0.283

0.281

1.29

1.01

1.96

2.50

NM_007719

CCR7

0.553

0.429

1.311

1.633

1.29

0.80

2.37

3.81

AF102269

CX3CR1

0.031

0.034

0.080

0.061

0.94

1.31

2.55

1.83

NM_008349

IL-10Rß

0.407

0.410

0.678

0.558

0.99

1.22

1.67

1.36

NM_008358

IL-15Rα

0.220

0.232

0.142

0.121

0.95

1.18

0.65

0.52

NM_010551

IL-16

0.033

0.027

0.032

0.029

1.22

1.10

0.98

1.08

X01450

IL-1α

0.761

0.911

0.849

0.918

0.84

0.92

1.11

1.01

M15131

IL-1ß

0.070

0.060

0.153

0.155

1.18

0.98

2.18

2.61

NM_008362

IL-1RI

0.069

0.077

0.074

0.053

0.90

1.41

1.07

0.69

NM_010555

IL-1RII

0.055

0.041

0.034

0.037

1.34

0.91

0.62

0.92

K02292

IL-2

0.020

0.024

0.013

0.015

0.82

0.87

0.67

0.63

D13565

IL-2 Rγ

0.020

0.013

0.071

0.061

1.53

1.16

3.47

4.56

NM_010558

IL-5

0.018

0.017

0.006

0.011

1.11

0.57

0.35

0.68

J03783

IL-6

0.031

0.020

0.019

0.019

1.53

1.00

0.61

0.94

NM_010560

gp130

0.056

0.045

0.047

0.046

1.25

1.03

0.84

1.02

NM_008373

IL-9

0.036

0.032

0.047

0.050

1.12

0.94

1.31

1.57

L10613

MIF

0.071

0.064

0.044

0.051

1.12

0.87

0.62

0.80

U26426

Eotaxin (Scya11)

0.448

0.347

0.312

0.258

1.29

1.21

0.70

0.74

NM_011331

MCP-5 (Scya12)

0.394

0.268

1.174

1.007

1.47

1.17

2.98

3.76

U86357

TECK (Scya25 )

0.937

1.170

0.618

0.650

0.80

0.95

0.66

0.56

X12531

MIP-1α (Scya3L1)

0.115

0.098

0.177

0.153

1.17

1.16

1.54

1.56

NM_009139

Scya6

0.061

0.052

0.081

0.075

1.16

1.09

1.34

1.43

AF128193

Scya7

0.021

0.024

0.023

0.025

0.87

0.93

1.10

1.03

U49513

MIP-1γ (Scya15)

0.031

0.029

0.043

0.033

1.10

1.30

1.37

1.15

M33266

IP-10 (Scyb10)

0.042

0.048

0.054

0.047

0.86

1.16

1.31

0.97

AF167354

Chemokine IP-9/ Scyb11

0.040

0.031

0.031

0.031

1.30

1.00

0.77

1.01

AF044196

BLC/BCA-1

0.013

0.010

0.085

0.115

1.26

0.73

6.51

11.19

AF252873

BRAK (MIP-2γ) (Kec)

0.104

0.088

0.051

0.075

1.18

0.68

0.49

0.85

AF071549

Fractalkine

0.067

0.065

0.035

0.039

1.03

0.91

0.53

0.60

L12029

SDF-1α

0.027

0.024

0.028

0.035

1.11

0.80

1.02

1.42

NM_009143

SDF-2

0.049

0.055

0.043

0.035

0.90

1.22

0.87

0.64

The expression levels normalized by ß-actin and the ratios of gene expression for 35 detected genes except for IL-18 and TGF-ß3 are shown. The values were calculated as described in Materials & Methods. Abbreviations used in this table are: CXCR, CXC chemokine receptor; CCR, CC chemokine receptor; CX3CR, CX3C chemokine (fractalkine) receptor; MIF, migration inhibitory factor; Scy, small inducible cytokine; MCP, monocyte chemoattractant protein; TECK, thymus-expressed chemokine; MIP, macrophage inflammatory protein; IP, IFN-γ infucible protein; BLC, B lymphocyte chemoattractant; BCA, B cell attracting chemokine; SDF, stromal cell derived factor.